This site is intended for UK-registered healthcare professionals only
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Prescribing Information and adverse events reporting information can be found at the bottom of this page.

This website has been developed and funded by A. Menarini Farmaceutica Internazionale SRL. The Improving Diabetes Steering Committee is supported by A. Menarini Farmaceutica Internazionale SRL. The SGLT2 Inhibitor Prescribing Decision Tool has been independently prepared by the IDSC. The media partners for this activity are GPnotebook and Diabetes on the net. GPnotebook and Diabetes on the net have had no input into the content of this website.

Bridging the gap between type 2 diabetes guidelines and prescribing practices

The Improving Diabetes Steering Committee (IDSC) – a multidisciplinary group of experts across primary and secondary care – aims to support healthcare professionals by producing materials that provide balanced reviews of the evidence and guidelines relating to use of SGLT2 inhibitors in the management of type 2 diabetes, including their risk/benefit profile in reducing the risk of cardiovascular, renal and metabolic (CVRM) complications.

The tools and resources developed by the IDSC and collated in this hub aim to build greater confidence regarding the use of SGLT2 inhibitors in type 2 diabetes management, helping to bridge the gap between current guidelines and prescribing practices.

SGLT2 Inhibitor
Prescribing Decision Tool

Use our evidence-led, interactive SGLT2 Inhibitor Prescribing Decision Tool for a quick reference guide that supports you in making appropriate prescribing decisions in clinical practice.

The handy traffic light system provides clarity regarding common areas of confusion, including the early and late use of SGLT2 inhibitors and complication risk.

Click here to use the SGLT2 Inhibitor Prescribing Decision Tool

The SGLT2 Inhibitor Prescribing Decision Tool has been independently prepared by the IDSC. A. Menarini Farmaceutica Internazionale SRL has fully funded the development of the SGLT2 Inhibitor Prescribing Decision Tool wallchart.

SGLT2 inhibitors: the new standard of care for cardiovascular, renal and metabolic protection in type 2 diabetes – a new narrative review

The IDSC has published five narrative reviews1–5 that reflect the growing evidence surrounding SGLT2 inhibitors in type 2 diabetes and aim to translate these evidence into clinical practice.

The most recent narrative review5 summarises the value of SGLT2 inhibitors in treating cardiovascular, renal and metabolic diseases, and places the relative risks into context.

Click here to read the full review

Implementing SGLT2 inhibitor therapy in line with the new NICE guidelines for type 2 diabetes management – a new narrative review

The IDSC has published six narrative reviews1–6 that reflect the growing evidence surrounding SGLT2 inhibitors in type 2 diabetes and aim to translate this evidence into clinical practice.

The most recent narrative review6 addresses real-world under-prescribing, provides practical guidance and an updated decision tool to help healthcare professionals implement the latest NICE guidelines, which prioritise SGLT2 inhibitors alongside metformin as preferred first-line therapy for type 2 diabetes.
Click here to read the full review

The above link will direct you to a third-party website. A. Menarini Farmaceutica Internazionale SRL and the media partners have had no input into the content of this website.

IDSC: Improving Diabetes Steering Committee; NICE: National Institute for Health and Care Excellence; SGLT2: sodium-glucose co-transporter-2

Hear from the IDSC

What are the outputs of the IDSC and how do they benefit people living with type 2 diabetes?

Professor John Wilding

Chair of the Improving Diabetes Steering Committee; Professor of Medicine, University of Liverpool

Join Lisa Kelly as she interviews Professor John Wilding on his role in the IDSC, their previous and most recent outputs, and how the materials they produce aim to benefit both healthcare professionals and people living with type 2 diabetes.

How can IDSC initiatives benefit both patients and healthcare providers in primary and secondary care?

Phillip Newland-Jones

Consultant Pharmacist in Diabetes and Endocrinology, University Hospitals Southampton NHS Foundation Trust

Watch Lisa Kelly and Phillip Newland-Jones discuss the importance of concomitant treatment in diabetes and other cardiorenal metabolic diseases, and how the tools developed by the IDSC can help both healthcare professionals and patients with type 2 diabetes.

Bringing expertise together: How did the IDSC interdisciplinary team collaborate to create practical tools for type 2 diabetes?

Jane Diggle

Specialist Diabetes Nurse Practitioner, College Lane Surgery, West Yorkshire

Jane Diggle discusses her involvement with the IDSC, and the outputs and impact this interdisciplinary expert group has had in the diabetes landscape.

Nephrology and type 2 diabetes: Insights from an IDSC nephrologist

Professor David Wheeler

Professor of Kidney Medicine at UCL & Consultant Nephrologist, The Royal Free, University College London

Hear Lisa Kelly and Professor David Wheeler discuss the latest guideline-based narrative review by the IDSC, and the link between diabetes and kidney disease.

If you are watching or listening to these videos, please ensure the content cannot be viewed or overheard by the general public

Meet the IDSC

John PH Wilding (IDSC CHAIR)

Department of Cardiovascular and Metabolic Medicine, Institute of Life Course and Medical Sciences, University of Liverpool, UK

Jane Diggle

College Lane Surgery, Ackworth, West Yorkshire, UK

Rahul Mohan

Nottinghamshire, UK

Samuel Seidu

Diabetes Research Centre, University of Leicester, Leicester General Hospital, UK

Marc Evans

University Hospital Llandough, Cardiff, UK

Debbie Hicks

Trend Diabetes, UK

Beth Kelly

Wiltshire, UK

Kevin Fernando

North Berwick Health Centre, North Berwick, UK

Naresh Kanumilli

Brooklands Northenden Primary Care Network, Manchester; Manchester University Foundation Trust, UK

Dipesh Patel

University College London, London, UK

Partha Kar

Portsmouth Hospitals NHS Trust, UK

Sarah Davies

Woodlands Medical Centre, Cardiff, UK

Nicola Milne

Brooklands Northenden Primary Care Network, Manchester, UK

David Wheeler

The Royal Free, University College London, UK

Philip Newland-Jones

University Hospitals Southampton NHS Foundation Trust, UK

Adie Viljoen

Borthwick Diabetes Research Unit, Lister Hospital, Stevenage, UK

CVRM: cardiovascular, renal and metabolic; IDSC: Improving Diabetes Steering Committee; NICE: National Institute for Health and Care Excellence; SGLT2: sodium-glucose co-transporter-2

References
  1. Wilding J, et al. Diabetes Ther. 2018; 9:1757–1773
  2. Ali A, et al. Diabetes Ther. 2019; 10:1595–1622
  3. Wheeler DC, et al. Diabetes Ther. 2020; 11:2757–2774
  4. Wilding JPH, et al. Diabetes Ther. 2022; 13:847–872
  5. Seidu S, et al. Diabetes Ther. 2024; 15:1099–1124
  6. Newland-Jones P, et al. Diabetes Ther. 2026; doi: 10.1007/s13300-026-01889-x

Invokana® (canagliflozin) is indicated for the treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise:

  • As monotherapy when metformin is considered inappropriate due to intolerance or contraindications
  • In addition to other medicinal products for the treatment of diabetes

For study results with respect to combination of therapies, effects on glycaemic control, cardiovascular and renal events, and the populations studied, please refer to section 4.4, 4.5 and 5.1 of the Invokana SmPC.

Click here
 for Invokana® (canagliflozin) United Kingdom Prescribing Information.

This website has been developed and funded by A. Menarini Farmaceutica Internazionale SRL. The Improving Diabetes Steering Committee is supported by A. Menarini Farmaceutica Internazionale SRL. The SGLT2 Inhibitor Prescribing Decision Tool has been independently prepared by the IDSC. The media partners for this activity are GPnotebook and Diabetes on the net. GPnotebook and Diabetes on the net have had no input into the content of this website.

Adverse events should be reported. Reporting forms and information can be found at https://yellowcard.mhra.gov.uk/. Adverse events should also be reported to A. Menarini Farmaceutica Internazionale SRL on 0800 085 8678 or by e-mail: [email protected]

PP-IN-UK-1449 v3 | September 2026

A. Menarini Farmaceutica Internazionale SRL have had no input into the contents of the footer and are not affiliated with the links. GPnotebook is responsible for the contents of the footer.

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